Take I-24E to Murfreesboro to exit 76 and go left on Medical Center Parkway for 4 miles to Memorial Blvd.  Turn left on Memorial and go .5 miles to Clark Blvd., turning right on E. Clark.  Continue for 1.1 miles; street name changes to Middle Tennessee Blvd.  Go 101 miles to East Main Street and Turn Left. Main campus entrance is on your left on Old Main Circle.  Public Safety is 0.1 miles on your right.

From Chattanooga:

Take I-24w toward Nashville, Murfreesboro exit 81.  Turn right on Church Street (US-231N).  Drive 0.9 miles and turn right onto Middle Tennessee Blvd.  Go another 1.9 miles and turn right onto Main Street.    Main campus entrance is on your left on Old Main Circle.  Public Safety is 0.1 miles on your right.

From Knoxville:

Take I-40W to Nashville/Lebanon and exit #235 onto 840W.  Take the Murfreesboro/Smyrna exit (US41S/US-70S).  Merge onto US-41S/US-70S (Broad Street).  Drive 4.5 miles and turn left onto West Main Street.  To another 1.5 miles.  Main campus entrance in on you right.  Public Safety is 0.1 miles on your left before the main campus entrance.

From Columbia:

Take I-65N to TN 840E (exit #59).  Take exit #53A onto I-24E towards Chattanooga.  Take either exit #76 or #78B and follow the directions from Nashville above.

From Memphis:

Take I-40E to Nashville and then I-440 to I-24E.  Continue using directions from Nashville (above)